Small intestinal bacterial overgrowth as a cause for irritable bowel syndrome

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Irritable bowel syndrome and small intestinal bacterial overgrowth.

In the last 3 decades, there has been a growing appreciation for the role of gut bacteria in gastrointestinal disease. Although inflammatory bowel disease and peptic ulcer disease have established a role for gut bacteria for more than 20 years, there is now increasing evidence that intestinal bacteria may play a role in irritable bowel syndrome as well. In this review, the current evidence for ...

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Small Intestinal Bacterial Overgrowth is Associated to Symptoms in Irritable Bowel Syndrome. Evidence from a Multicentre Study in Romania. Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome

IOANA G. MORARU1, A.G. MORARU, M. ANDREI, IRINA CIORTESCU, P. PORR, T. IORDACHE, V. DRUG, M. DICULESCU, P. PORTINCASA, D.L. DUMITRASCU 12 Medical Department, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania 2Department of Gastroenterology, Clinical Emergency Hospital, Brasov, Romania 3Gastroenterology Department, “Elias” Clinical University Emergency Hospital, Buchare...

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Small intestinal bacterial overgrowth: a framework for understanding irritable bowel syndrome.

CONTEXT Irritable bowel syndrome (IBS), which affects 11% to 14% of the population, is a puzzling condition with multiple models of pathophysiology including altered motility, visceral hypersensitivity, abnormal brain-gut interaction, autonomic dysfunction, and immune activation. Although no conceptual framework accounts for all the symptoms and observations in IBS, a unifying explanation may e...

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The Relationship between Small-Intestinal Bacterial Overgrowth and Intestinal Permeability in Patients with Irritable Bowel Syndrome

BACKGROUND/AIMS Small-intestinal bacterial overgrowth (SIBO) is a frequent finding in patients with irritable bowel syndrome (IBS). Many patients with IBS also have abnormal intestinal permeability, which is probably due to low-grade inflammation in the intestinal mucosa. Our aim was to verify the relationship between SIBO and small-intestinal permeability in IBS patients. METHODS A cohort of...

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Small Intestinal Bacterial Overgrowth is Associated with Intestinal Inflammation in the Irritable Bowel Syndrome

BACKGROUND AND AIM Small intestinal bacterial overgrowth is encountered in bowel disorders, including irritable bowel symptoms. Low degrees of inflammation have been recently reported in the irritable bowel syndrome. We looked for the association between intestinal inflammation and small intestinal bacterial overgrowth in irritable bowel syndrome. METHODS Small intestinal bacterial overgrowth...

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ژورنال

عنوان ژورنال: Current Opinion in Gastroenterology

سال: 2017

ISSN: 0267-1379

DOI: 10.1097/mog.0000000000000348